(Anat.) The whitish mass of soft matter (the center of the nervous system, and the seat of consciousness and volition) which is inclosed in the cartilaginous or bony cranium of vertebrate animals. It is simply the anterior termination of the spinal cord, and is developed from three embryonic vesicles, whose cavities are connected with the central canal of the cord; the cavities of the vesicles become the central cavities, or ventricles, and the walls thicken unequally and become the three segments, the fore-, mid-, and hind-brain. Note: In the brain of man the cerebral lobes, or largest part of the forebrain, are enormously developed so as to overhang the cerebellum, the great lobe of the hindbrain, and completely cover the lobes of the midbrain. The surface of the cerebrum is divided into irregular ridges, or convolutions, separated by grooves (the so-called fissures and sulci), and the two hemispheres are connected at the bottom of the longitudinal fissure by a great transverse band of nervous matter, the corpus callosum, while the two halves of the cerebellum are connected on the under side of the brain by the bridge, or pons Varolii.