1.(Anat.) The tissue which fills the cavities of most bones; the medulla. In the larger cavities it is commonly very fatty, but in the smaller cavities it is much less fatty, and red or reddish in color.
2.The essence; the best part. "It takes from our achievements... The pith and marrow of our attribute."
3.One of a pair; a match; a companion; an intimate associate. (Scot.) "Chopping and changing I can not commend, With thief or his marrow, for fear of ill end."