... had reached the Rappahannock and the Potomac by 1650, and settlers began moving into Lancaster County. In 1653 the first settlers established themselves in what is now King William County. Just before the end of the seventeenth century the tobacco industry had expanded into the lowlands all along the Rappahannock and Potomac rivers below the Fall Line. In 1689 the York River area produced the largest quantity of tobacco, the Rappahannock River area was second, the Upper James third, and the Accomac Peninsula last. While the production ... — Tobacco in Colonial Virginia - "The Sovereign Remedy" • Melvin Herndon