Free translatorFree translator
Synonyms, antonyms, pronunciation

  Home
English Dictionary      examples: 'day', 'get rid of', 'New York Bay'




Rofecoxib   Listen
noun
rofecoxib  n.  (Chem. & Med.) A chemical substance (C17H14O4S, molecular weight 314.36) used in medicine as an analgesic to alleviate pain and inflammation; it is a synthetic compound, and is marketed by Merck & Co. under the trade name Vioxx, in tablets giving dosages of 12.5 or 25 milligrams. It is classed as a non-steroidal anti-inflammatory drug (NSAID). Chemically, it is 4-(4-(methylsulfony)phenyl)-3-phenyl-2(5H) furanone. Its chemical structure contains two phenyl rings and a furanone ring. It is believed to act by inhibition of prostaglandin biosynthesis, through inhibition of the enzyme cyclooxygenase-2 (COX-2); unlike aspirin, it does not inhibit cyclooxygenase-1.






Collaborative International Dictionary of English 0.48








Advanced search
     Find words:
Starting with
Ending with
Containing
Matching a pattern  

Synonyms
Antonyms
Quotes
Words linked to  

only single words



Share |





Words linked to "Rofecoxib" :   Vioxx



Copyright © 2024 Free Translator.org